Table 2. Antimicrobial drug resistance profiles before and after transfer of NDM-1-–ncoding plasmid from Vibrio fluvialis strains to other bacterial species in study of diarrheal fecal samples from patients in Kolkata, India, May 2009–September 2013*.
| Isolate no. |
Test isolate |
Resistance profile
of wild type |
Resistance profile
of transconjugant |
MIC IPM, μg/mL† |
Frequency of transfer |
| J53-Na-Azide | Escherichia coli | – | AMP, CRO, SXT, CXM, CTX | 3 | 8.7 × 105 |
| BCH 04216 | EAEC | AMP, ERY, SXT, NA, CXM, CTX | AMP, E, SXT, NA, CXM, CTX, CRO | 3 | 5.9 × 105 |
| IDH 04184 | EPEC | AMP, ERY, OFX, NOR, SXT, NA, CIP | AMP, E, OFX, NOR, SXT, NA, CIP, CRO, CXM, CTX | 1.5 | 2.7 × 105 |
| IDH 06412 | ETEC | AMP, ERY, NA, SXT | AMP, E, NA, SXT, CRO, CXM, CTX | 3 | 7.5 × 105 |
| BCH 0704 | Salmonella Bareilly | – | AMP, CRO, SXT, CXM, CTX | 3 | 1.7 × 103 |
| 570764 | Salmonella Newport | – | AMP, CRO, SXT, CXM, CTX | 3 | 1.4 × 103 |
| IDH 06370 | Shigella dysenteriae 12 | AMP, STR, NA | AMP, STR, NA, CRO, SXT, CXM, CTX | 1.5 | 2.4 × 103 |
| IDH 06498 | Shigella flexneri 4 | AMP, E, STR, SXT | AMP, E, STR, SXT, CRO, CXM, CTX | 3 | 4.4 × 103 |
| IDH 06342 | Shigella flexneri 1b | AMP, E, NA, STR, SXT | AMP, E, NA, STR, SXT, CRO, CXM, CTX | 0.75 | 1.9 × 103 |
| IDH 03988 | V. parahaemolyticus | AMP | AMP, CRO, SXT, CXM, CTX | 0.50 | 5.7 × 105 |
*Antibiogram in bold among transconjugants denote acquired resistance phenotypes from V. fluvialis IDH05720 after conjugation. AMP, ampicillin; CIP, ciprofloxacin; CRO, ceftriaxone; CTX, cefotaxime; CXM, cefuroxime; EAEC, enteroaggressive E. coli; EPEC, enteropathogenic E. coli; ERY, erythromycin; ETEC, enterotoxigenic E. coli; NA, nalidixic acid; NDM-1, New Delhi metallo-β-lactamase; NOR, norfolxacin; OFX, ofloxacin; STR, streptomycin, SXT, sulfamethoxxozole. †MIC for imepenium. MIC denotes values of imepenium across different pathogens that were used as transconjugants.