Table II.
Comparison of FOXM1 and Hh signaling molecules in tumors and normal tissues.
| Squamous cell carcinoma | Adenocarcinoma | ||||
|---|---|---|---|---|---|
| Protein | IOD (mean ± SD) | P-valuea | IOD (mean ± SD) | P-valueb | P-valuec |
| FOXM1 | (2.27±1.64)×105 | <0.001 | (1.39±1.17)×105 | 0.014 | 0.340 |
| SHh | (3.27±0.95)×105 | <0.001 | (3.38±0.37)×105 | 0.007 | 0.743 |
| SMO | (1.89±1.16)×105 | <0.001 | (1.58±0.84)×105 | 0.007 | 0.743 |
| GLI1 | (1.33±0.96)×105 | <0.001 | (1.41±0.73)×105 | 0.014 | 0.620 |
| PTCH1 | (1.71±0.58)×105 | <0.001 | (1.97±0.17)×105 | 0.007 | 0.236 |
a
Squamous cell carcinoma compared with normal tissues.
b
Adenocarcinoma compared with normal tissues.
c
Squamous cell carcinoma compared with adenocarcinoma. FOXM1, forkhead box M1; Hh, hedgehog; SHh, Sonic Hh; SMO, smoothened; GLI1, glioma-associated oncogene 1; PTCH1, patched 1; IOD, integrated optical density; SD, standard deviation.