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. 2016 Aug 8;12(4):2648–2656. doi: 10.3892/ol.2016.4969

Table II.

Univariate prognostic analysis of overall and disease-free survival rates in patients with hepatocellular carcinoma.

Overall survival rate Disease-free survival rate


Variable n 3-year, % 5-year, % P-value 3-year, % 5-year, % P-value
Gender 0.891 0.895
  Female 18 82.4 51.0 82.4 44.9
  Male 56 78.2 50.1 74.6 44.5
Age, years 0.644 0.732
  ≤45 17 81.3 68.8 75.6 56.7
  >45 57 78.6 44.7 76.8 41.1
HBsAg status 0.079 0.073
  Negative 6 50.0 33.3 50.0 33.3
  Positive 68 81.9 52.0 78.9 45.7
Cirrhosis 0.235 0.318
  No 12 66.7 50.0 66.7 50.0
  Yes 62 81.8 50.4 78.5 43.5
AFP, µg/l 0.122 0.224
  ≤400 29 68.1 41.0 64.7 33.2
  >400 45 86.4 56.3 84.1 51.8
Tumor size, cm 0.764 0.778
  ≤5 26 60.1 47.5 60.4 47.7
  >5 48 89.4 52.0 85.2 47.8
Tumor number <0.001a <0.001a
  Single 47 95.7 58.3 93.6 56.3
  Multiple 27 48.4 36.3 44.9 23.0
Tumor capsule 0.739 0.715
  Complete 52 76.5 44.0 72.6 44.3
  Incomplete 22 85.7 66.0 85.7 45.7
Vascular infiltration 0.035a 0.049a
  No 54 92.4 54.1 90.5 50.2
  Yes 20 45.0 40.0 45.0 30.0
Edmondson grade <0.001a <0.001a
  I/II 48 93.7 56.4 93.7 54.5
  III/IV 26 46.3 37.9 42.6 25.6
TNM Stage 0.020a 0.027a
  I/II 45 93.3 54.1 91.1 47.3
  III/IV 29 48.5 40.7 45.2 32.9
BCAT1 protein level 0.004a 0.004a
  Low 37 94.6 66.8 94.6 58.5
  High 37 60.3 33.2 57.7 30.5
a

P<0.05. HbsAg, hepatitis B surface antigen; BCAT1, branched-chain amino acid transaminase 1; TNM, tumor-node-metastasis; AFP, α-fetoprotein.