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. 2016 Aug 4;12(4):2191–2195. doi: 10.3892/etm.2016.3572

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Figure 3. — TGF-βRII silencing abolished the effects of DCN on the TGF-β signaling pathway and HepG2 cell proliferation. (A) TGF-βRII was silenced with siRNA in HepG2 cells. (B) Protein expression of pTGF-βRI was detected by western blot analysis in HepG2 cells subjected to DCN transfection and/or TGF-βRII silencing. (C) Cell proliferation of HepG2 cells subjected to DCN transfection and/or TGF-βRII silencing was assessed by MTT assay. Data are expressed as the mean ± standard deviation. *P<0.05 vs. control group; ^#P<0.05, vs. DCN group. Ctrl or Control, untreated group; DCN, decorin-transfected group; siRNA, mismatch-siRNA-transfected group; DCN+siRNA, DCN+siRNA-transfected group; TGF-βR, transforming growth factor-β receptor; pTGF-βRI, phosphorylated TGF-βRI; siRNA, small interfering RNA; Ctrl, control.