Table I.
Characteristics of 53 patients with nasopharyngeal carcinoma who had post-radiation nasopharyngeal necrosis.
| Characteristic | UPRNN |
|---|---|
| Age (years) | |
| Mean ± SD | 46.75±6.82 |
| Gender | |
| Male | 32 |
| Female | 21 |
| BMI | |
| Mean ± SD | 23.47±2.67 |
| Prescriptive dose of ulcer zone (Gy) | |
| Mean ± SD | 70.59±2.36 |
| T stage | |
| T1 | 0 |
| T2 | 2 |
| T3 | 36 |
| T4 | 15 |
| Sites of involvementb | |
| 1–3 | 24 |
| >3 | 29 |
| Grades of ulcer | |
| Mild | 4 |
| Moderate | 27 |
| Severe | 22 |
| Chemotherapy | |
| Neo-CT | 34 |
| Concurrent | 18 |
| Adjuvant | 12 |
| Response of neo-CT | |
| SD | 22 |
| PR | 12 |
| CR | 0 |
| Intervala (months) | |
| Mean ± SD | 2.92±1.26 |
| Outcome of UPRNN | |
| Alive | 48 |
| Succumbed to mortality | 5 |
a
The interval from the completion of radiotherapy to the diagnosis of ulcer of post-radiation nasopharyngeal necrosis.
b
The sites of involvement included the medial pterygoid muscle, lateral pterygoid muscle, parapharyngeal space, musculus longus capitis and the skull base. BMI, body mass index; neo-CT, neoadjuvant chemotherapy; SD, stable disease; PR, partial response; CR, complete response; SD, standard deviation; UPRNN, ulcer of post-radiation nasopharyngeal necrosis.