Table 1. The Clinicopathological Characteristics of HPV-Positive and HPV-Negative Patients.
| Characteristic | HPV Positive (N = 15) | HPV Negative (N = 99) | P Value |
|---|---|---|---|
| Sex | 0.838 | ||
| Male | 8 (53.3) | 50 (51) | |
| Female | 7 (46.7) | 49 (49) | |
| Age, y | 0.509 | ||
| < 50 | 3 (20.0) | 27 (27.3) | |
| 70 - 50 | 6 (40.0) | 42 (42.4) | |
| > 70 | 6 (40.0) | 30 (30.3) | |
| Location | 0.879 | ||
| Tongue | 10 (66.6) | 65 (65.7) | |
| Buccal mucosa | 0 (0.0) | 18 (18.2) | |
| Alveolar ridge | 3 (20.0) | 9 (9.1) | |
| Palate | 1 (6.7) | 3 (3.0) | |
| Floor of the mouth | 1 (6.7) | 2 (2.0) | |
| Lip | 0 (0.0) | 2 (2.0) | |
| Grade | 0.274 | ||
| 1 | 6 (40.0) | 59 (59.6) | |
| 2 | 9 (60.0) | 33 (33.3) | |
| 3 | 0 (0.0) | 7 (7.1) | |
| T classification | 0.406 | ||
| T1 | 3 (20.0) | 3 3(33.3) | |
| T2 | 6 (40.0) | 32 (32.3) | |
| T3 | 2 (13.3) | 12 (12.1) | |
| T4 | 4 (26.7) | 22 (22.2) | |
| N classification | 0.045 | ||
| N0 | 5 (33.3) | 55 (55.6) | |
| N1 | 1 (6.7) | 18 (18.2) | |
| N2 | 8 (53.3) | 22 (22.2) | |
| N3 | 0 (0.0) | 1 (1.0) | |
| NX | 1 (6.7) | 3 (3.0) | |
| Stage | 0.04 | ||
| I | 3 (20.0) | 25 (25.3) | |
| II | 1 (6.7) | 17 (17.2) | |
| III | 1 (6.7) | 22 (22.2) | |
| IV | 10 (66.7) | 35 (35.4) | |
| Smoking history | 0.99 | ||
| Never | 7 (46.6) | 42 (42.5) | |
| Ever | 4 (26.7) | 29 (29.3) | |
| Unknown | 4 (26.7) | 28 (28.2) |