Table 2. Comparison of the Two Groups According to Treatment Protocols and Outcomesa.
| HPV Positive (N = 15) | HPV Negative (N = 99) | P Value | |
|---|---|---|---|
| Treatment protocol | 0.67 | ||
| Only surgery | 3 (25) | 14 (15.8) | |
| Surgery + Adjuvant radiation therapy | 8 (66.7) | 65 (73) | |
| Surgery + Adjuvant chemoradiation | 1 (8.3) | 5 (5.6) | |
| Neoadjuvant (radiation therapy ± chemotherapy) | 0 | 5 (5.6) | |
| Events | 0.89 | ||
| Recurrence free | 10 (66.7) | 61 (61.6) | |
| Local recurrence | 3 (22) | 24 (24.2) | |
| Regional recurrence | 2 (13.3) | 8 (8.1) | |
| Locoregional recurrence | 0 | 3 (3) | |
| Distant metastasis | 0 | 2 (2) | |
| Second primary cancer | 0 | 1 (1) | |
| Patient’s status | 0.004 | ||
| Alive | 4 (26.7) | 65 (65.7) | |
| Dead | 11 (73.3) | 34 (34.3) | |
| Median disease free survival rate, mo | 13.9 | 49.9 | 0.029 |
| Median overall survival rate, mo | 15.7 | 49.6 | 0.017 |
aValues are expressed as No. (%).