Figure 4.
Multivariate adaptive regression splines model for nucleotide +103. The model suggests that the level of cadherin 1 gene expression decreases as the methylation in nucleotide+103 increases up to ~10%; above the cut-off, a saturation (plateau) appears. CDH1, cadherin 1; nt, nucleotide; SE, standard error; MARS, multivariate adaptive regression splines.