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. 2016 Sep 1;12(4):2568–2576. doi: 10.3892/etm.2016.3647

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Copyright: © Du et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Effect of opioid treatment on the PWTs in an animal model of bone cancer pain. The analgesic effect of morphine on allodynia was stronger than that of β-EP. *P<0.05 and **P<0.01 vs. the sham surgery group; ^ΔΔP<0.01 vs. the surgery group; ^••P<0.01 vs. the morphine group. n=8–10. PWTs, paw withdrawal thresholds; β-EP, β-endorphin; 6d, 6 day.