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Mice were fed CTR, Chol, EtOH and EtOH+Chol diets for 3 months. A, XBP-1 mRNA detected by RT-qPCR. Values are means ± S.E.M. a, p < 0.05 vs CTR; b, p < 0.05 vs Chol; c, p < 0.05 vs EtOH (n = 4 per group). B, representative immunoblots of 4-HNE adducts and actin (n = 4 per group).
