Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose-dependent effect of various purines on extracellular Aβ42 and Aβ40 production in N2a-AβPP695 cells. Cells were exposed to various concentrations of compounds 1–6, 8 for 18 h. Extracellular Aβ42 (upper panel) and Aβ40 (lower panel) levels were measured by an ELISA assay and are expressed as fold change over the level of control, vehicle-treated cells. Representative of two independent experiments, errors bars represent standard deviation of triplicate values.
