Figure 6.

Effect of a treatment associating the P1 peptide with TMZ in a swiss nude mice model of established tumors. A. Design of the experiment. Tumor establishment indicates that 2.10⁶ PCTC-GBM were injected to form a tumor of which the volume was equal to 100mm³±33.3. Then, mice were treated with indicated treatment. D: day, w: week, it: intra-tumoral, ip: Intraperitoneal. B. Graph illustrates the impact of the 4 considered treatments on tumor weight of established tumors. Open circles represent mice. Black circles represent the average±standard deviation obtained for each treatment. p values were obtained by performing a t test.