Table 3.
Analysis of mutation status in plasma with ddPCR.
| Patient | Mutation fraction (mutant/wild type, copies/μl) | |||
|---|---|---|---|---|
| TP53 (c.747G>T) | TERT (c.1-124C>T) | CTNNB1 (c.121A>G) | CTNNB1 (c.133T>C) | |
| H04 | 0.33% (0.1/30.3) | 7.0% (4.3/61.8) | Negative | Negative |
| H06 | Negative | Negative | 11.5% (1.9/16.5) | Negative |
| H09 | Negative | Negative | 9.2% (1.8/19.6) | Negative |
| H10 | 1.0% (0.1/9.6) | Negative | Negative | Negative |
| H20 | Negative | 0.55% (0.07/12.8) | Negative | Negative |
| H23 | Negative | 7.2% (1.2/16.6) | Negative | Negative |
| H32 | Negative | 0.67% (0.07/10.4) | Negative | Negative |
| H35 | 1.8% (0.11/6.2) | Negative | Negative | Negative |
| H41 | 3.2% (0.1/3.1) | 0.89% (0.07/7.9) | Negative | Negative |
| H43 | Negative | 0.63% (0.08/12.8) | 21.6% (3/13.9) | Negative |
| H47 | Negative | 1.4% (0.07/4.9) | Negative | Negative |
| H50 | Negative | Negative | Negative | 2.3% (0.34/14.6) |
| H51 | Negative | Negative | 18.9% (1.7/9) | Negative |
| H52 | Negative | 3.3% (0.08/2.4) | Negative | Negative |
| H53 | 0.55% (0.11/20.1) | Negative | Negative | Negative |
| H57 | Negative | Negative | Negative | 0.82% (0.1/12.2) |
| H58 | Negative | 1.3% (0.07/5.6) | Negative | Negative |
| H59 | 10% (0.6/6) | Negative | Negative | Negative |
| H61 | Negative | Negative | Negative | 16.5% (1.7/10.3) |
| H62 | Negative | Negative | Negative | 13.6% (0.6/4.4) |
| H63 | Negative | Negative | Negative | 20.3% (1.6/7.9) |
| H65 | Negative | Negative | Negative | 23.2% (2.2/9.5) |
| H66 | 23.2% (1.9/8.2) | Negative | Negative | Negative |
| H67 | Negative | Negative | 16.8% (6.8/40.4) | Negative |
| H68 | Negative | 0.92% (0.08/8.7) | Negative | Negative |
| H78 | Negative | 14.3% (0.77/5.4) | Negative | Negative |
| H79 | Negative | Negative | 23.7% (11/46.5) | Negative |