Table 4.
Hazard ratio for death from all causes in African Americans vs. Caucasians after initial surgical diagnosis of breast cancer stratified by the single variables of age (10 yr. increments), stage, grade, ER status, PR status, marital status or laterality.
| Variables | Hazard Ratio (Confidence Intervals) | p (Pearson Chi Square) | Number of patients (Caucasian /African American) |
Caucasians Percent in Category | African Americans Percent in category | African Americans/ Caucasians (Ratio to population) |
|---|---|---|---|---|---|---|
| All Patients | 1.37(1.34-1.40) | 0 | 341210/38462 | 0.113 | ||
| Age (10 year groupings) | ||||||
| 20 | 1.67 (1.09-2.56) | 0.0179 | 354/ 119 | 0.1 | 0.3 | 0.336 (2.97) |
| 30 | 1.64 (1.46-1.85) | < 10-6 | 6483/ 1382 | 1.9 | 3.6 | 0.213 (1.88) |
| 40 | 1.96 (1.85-2.07) | 0 | 45745/ 7141 | 13.4 | 18.6 | 0.156 (1.38) |
| 50 | 2.12 (2.02-2.23) | 0 | 74360/ 9727 | 21.8 | 25.3 | 0.131 (1.16) |
| 60 | 1.96 (1.87-2.05) | 0 | 92657/10163 | 27.2 | 26.4 | 0.110 (0.97) |
| 70 | 1.56 (1.48-1.64) | 0 | 62055/ 5519 | 18.2 | 14.3 | 0.089 (0.79) |
| 80 | 1.34 (1.25-1.41) | 0 | 49610/ 3690 | 14.5 | 9.6 | 0.074 (0.65) |
| 90 | 1.14 (1.03-1.25) | 0.0087 | 9946/ 721 | 2.9 | 1.9 | 0.072 (0.64) |
| Stage | ||||||
| I | 1.19 (1.14-1.24) | < 10-6 | 174851/14570 | 51.2 | 37.9 | 0.083 (0.73) |
| II | 1.31 (1.27-1.36) | 0 | 122530/16475 | 35.9 | 42.8 | 0.134 (1.19) |
| III | 1.49 (1.43-1.54) | 0 | 43829/ 7417 | 12.9 | 19.3 | 0.169 (1.50) |
| Grade | ||||||
| 1 | 1.29 (1.20-1.40) | < 10-6 | 67926/ 4272 | 19.9 | 11.1 | 0.063 (0.56) |
| 2 | 1.37 (1.32-1.42) | 0 | 149476/13492 | 43.8 | 35.1 | 0.090 (0.80) |
| 3 | 1.35 (1.31-1.39) | 0 | 123808/20698 | 36.3 | 53.8 | 0.167 (1.48) |
| ER status | ||||||
| + | 1.42 (1.38-1.46) | 0 | 272897/24422 | 80.0 | 63.5 | 0.089 (0.79) |
| - | 1.31 (1.26-1.35) | 0 | 68313/14040 | 20.0 | 36.5 | 0.206 (1.82) |
| PR status | ||||||
| + | 1.43 (1.38-1.47) | 0 | 237739/20501 | 69.7 | 53.3 | 0.086 (0.76) |
| - | 1.33 (1.29-1.37) | 0 | 103471/17961 | 30.3 | 46.7 | 0.174 (1.54) |
| Marital status | ||||||
| Single | 1.56 (1.49-1.63) | 0 | 38657/10605 | 11.3 | 27.6 | 0.274 (2.42) |
| Married | 1.57 (1.51-1.62) | 0 | 208943/15131 | 61.2 | 39.3 | 0.072 (0.64) |
| Separated | 1.43 (1.22-1.68) | 8.5 x 10-6 | 2699/ 868 | 0.8 | 2.3 | 0.322 (2.85) |
| Divorced | 1.39 (1.31-1.48) | 0 | 36026/ 5843 | 10.6 | 15.2 | 0.162 (1.43) |
| Widowed | 1.14 (1.10-1.19) | < 10-6 | 54885/ 6015 | 16.1 | 15.6 | 0.110 (0.97) |
| Laterality | ||||||
| Right | 1.46 (1.42-1.51) | 0 | 168235/18832 | 49.3 | 49.0 | 0.112 (0.99) |
| Left | 1.48 (1.43-1.52) | 0 | 172975/19630 | 50.7 | 51.0 | 0.113 (1.00) |
Ratio of African Americans to Caucasians in a category normalized to the ratio of African Americans to Caucasians in the population is indicated in bold if greater than 1.00.