Figure 5.

KEGG pathways with absolute value of principal component loadings (PC loadings)>0.1 in first three components. PC 1 module can be divided into module A and module B according to PC loadings, which indicated they play different role in PC 1 at contrast direction. Pathways in PC 2 module are consistently positive. PC 3 module was also divided into two sub-modules. PC 1 module and PC 2 module were able to separate cluster A,B and C from each other and identify cluster D & E from cluster A,B & C obviously, but they can hardly discriminate cluster D and E from each other. Pathways in PC 3 module showed no differences among cluster A,B & C, but they can be used to separate cluster D from E.