Table 3.

Univariate log-rank analyses.

Parameters	Category	No. of case	DSS		DMeFS		LRFS
			No. of event	p-value	No. of event	p-value	No. of event	p-value
Gender	Male	95	45	0.7870	38	0.6128	30	0.3240
	Female	29	14		11		7
Age (years)	<60 years	98	48	0.8600	42	0.3091	29	0.8206
	>=60 years	26	11		7		8
Primary tumor (pT)	T1-T2	80	32	0.0289*	25	0.0085*	19	0.0180*
	T3-T4	44	27		24		18
Nodal status (N)	N0-N1	56	18	0.0008*	17	0.0132*	12	0.0160*
	N2-N3	68	41		32		25
Stage	I-II	38	10	0.0020*	9	0.0072*	5	0.0026*
	III-IV	86	49		40		32
Histological grade	Keratinizing/Non-keratinizing	47	20	0.1980	17	0.2753	15	0.9521
	Undifferentiated	77	39		32		22
EBER	Negative	1	1	0.0577	1	0.0937	0	0.7305
	Positive	123	58		48		37
GAD1 Exp.	Low Exp. (H-score<median)	62	20	0.0002*	11	<0.0001*	12	0.0010*
	High Exp. (H-score>=median)	62	39		38		25

*, Statistically significant; DSS, disease-specific survival; DMeFS, distal metastasis-free Survival; LRFS, local recurrence-free survival