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. 2016 Sep 28;6:33963. doi: 10.1038/srep33963

Figure 8. Synergistic and antagonistic effects of components in Sini Decoction.

Figure 8

(A) Liquiritin (LQ) can alleviate the arrhythmia caused by aconitine (AC). (a–d) The arrhythmia monitored in the ECG after administration of aconitine and liquiritin. (e) Onset time and (f) dosage of arrhythmia after continuous administration of aconitine and liquiritin under PB, VT, and CA. For e and f, solid bars represent AC treatment alone and open bars represent AC + LQ co-treatment. (B) 6-gingerol can elevate the cardiac functions of aconitine by hemodynamic indexes. (a) LVEDP, (b) HR, (c) dp/dtmax, (d) SBP, DBP, MBP and LVSP after administration of aconitine (5 ug/kg) and 6-gingerol (70 ug/kg).) *p < 0.05, **p < 0.01 vs aconitine group. Data shows as mean ± SD.