Table 1. Information of top-3 drug-disease module pairs.
Rank | Drugs in drug module | Diseases in disease module | Number of drugs | Number of diseases | Density of drug module | Density of disease module | Score between drug-disease module pair |
---|---|---|---|---|---|---|---|
1 | thiothixene, | Parkinson Disease Secondary, | |||||
Tremor, | |||||||
chlorpromazine, | Dyskinesia Drug-Induced, | ||||||
fluphenazine, | Movement Disorders, | ||||||
perphenazine, | Parkinsonian Disorders, | 7 | 9 | 0.95 | 0.50 | 0.59 | |
prochlorperazine | Basal Ganglia Diseases, | ||||||
thioridazine, | Essential Tremor, | ||||||
trifluoperazine | Parkinson Disease, | ||||||
Hepatolenticular Degeneration | |||||||
2 | thiothixene, | Alcohol Withdrawal Delirium, | |||||
chlorpromazine, | Schizophrenia, | ||||||
fluphenazine, | Substance-Related Disorders, | ||||||
perphenazine, | Bipolar Disorder, | ||||||
prochlorperazine | Narcolepsy, | 7 | 8 | 0.95 | 0.71 | 0.39 | |
thioridazine, | Lewy Body Disease, | ||||||
trifluoperazine | Psychoses Substance-Induced, | ||||||
Psychotic Disorders | |||||||
3 | Alcoholism, | ||||||
Depressive Disorder Major, | |||||||
protriptyline, | Mood Disorders, | ||||||
imipramine, | Depressive Disorder, | ||||||
cyclobenzaprine, | Schizophrenia, | ||||||
nortriptyline, | Substance-Related Disorders, | ||||||
amoxapine, | Bipolar Disorder, | 7 | 12 | 0.95 | 0.50 | 0.36 | |
desipramine, | Personality Disorders, | ||||||
amitriptyline | Anxiety Disorders, | ||||||
Depression Postpartum, | |||||||
Dyssomnias, | |||||||
Sleep Disorders Circadian Rhythm |