Table 2.
Predicted percent of donors that will respond to MUC1-peptide immunization.
| Peptide Sequence | % of Donors with at Least 30% Cell Kill | 95% CI |
|---|---|---|
| SLAPPVHNV | 87.50% | 47.3%–99.7% |
| SLAPT(Tn)VHNV | 75% | 34.9%–96.8% |
| SLAPTVHNV | 62.50% | 24.5%–91.48% |
| SLSYTNPAV | 37.50% | 8.5%–75.5% |
| ALGSTAPPV | 12.50% | 0.32%–52.6% |
Estimation of the true proportion of donors who respond to the peptide and the corresponding 95% confidence interval: Based on considering 30% cell kill a response, it appears that at least 47% of donors receiving P15:SLAPPVHNV will respond and at least 35% of donors receiving P4:SLAPT(Tn)VHNV will respond.