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. 2016 Jul 27;6(3):25. doi: 10.3390/brainsci6030025

Figure 5.

Figure 5

Effects of restraint stress or WCE for hippocampal neuroimmune mRNAs. For CCL2, there was an overall effect of the treatments (F(2,34) = 10.54, p < 0.001) and a significant effect of WCE relative to stress or control. The trend toward a stress effect was not significant. Similarly, an overall trend toward a significant effect of treatments for TNFα was not significant (p = 0.07). For IL-1β, there was an overall significant effect of treatments (F(2,34) = 4.98, p < 0.05) with significant effects of stress and WCE relative to controls. Finally, there were no significant effects found with TLR4 mRNA. * p < 0.05, ** p < 0.01, **** p < 0.0001 versus Controls. A, B, C, and D delineate data for CCL2, TNFα, IL-1β and TLR4 mRNAs, respectively, (n = 9–13 per group).