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Inhibition of hookworm cysteine protease activity by K11777 and ODN. Soluble extracts of female (black bars) and male (grey bars) A. ceylanicum were incubated for 10 min with 1 μM inhibitor, as described in the text. Residual cysteine protease activity was measured with the fluorogenic substrate Z-Phe-Arg-AMC. Data were generated from two experiments each in duplicate; one experiment is shown.
