Table 1.

Inhibition of mammalian cysteine cathepsins and cruzain by CP inhibitors.

Inhibitor	Target Cathepsin and IC50 Value (nM)
	CatB	CatF	CatK	CatL	CatS	Cruzain
K11777	9	3	1.8	<0.2	<0.2	3.5
ODN	1034	n.t.	0.2	2995	60	n.t.

Data for K11777 from [45] and for ODN from [38] as cited in [45]. Each assay was performed twice; n.t. = not tested; Cruzain is a cathepsin l-like protease in Trypanosoma cruzi, the etiological agent of Chagas disease [46].