Table 3.
1H NMR data of compounds 3 and 4, δ in ppm, J in Hz.
| Position | 3 | 4 | ||
|---|---|---|---|---|
| In CDCl3 b | In Acetone-d6 b | In CDCl3 a | In Acetone-d6 b | |
| 1 | 2.38, dd (10.5, 8.4) | 2.42, dd (10.2, 9.0) | ||
| 3 | 1.93, dq (6.4, 7.2) | 1.76, dq (9.6, 7.2) | 2.32, q (7.2) | 2.27, q (7.2) |
| 4 | 3.63, dd (6.4, 5.6, 5.6) | 3.40, ddd (10.2, 9.6, 6.6) | ||
| 5 | β: 1.91, dd (13.2, 5.6) α: 2.28, dd (13.2, 5.6) |
β: 1.82, dd (12.6, 10.2) α: 2.24, dd (12.6, 6.6) |
5.82, d (1.8) | 5.69, d (1.8) |
| 7 | β: 2.45, d (10.0) α: 2.66, d (10.0) |
β: 2.45, d (10.0) α: 2.66, d (10.0) |
β: 2.71, dd (15.6, 1.8) α: 2.79, d (15.6) |
β: 2.75, d (15.6) α: 2.81, dd (15.6, 1.8) |
| 9 | β: 1.66, d (13.8) α: 1.86, dd (13.8, 1.2) |
β: 1.70, d (13.8) α: 1.85, dd (13.8, 1.2) |
||
| 11 | β: 2.38, d (10.0) α: 2.44, d (10.0) |
β: 2.39, d (10.0) α: 2.41, d (10.0) |
β: 1.46, dd (12.9, 10.5) α: 1.70, ddd (12.9, 8.4, 1.2) |
β: 1.51, dd (12.6, 10.2) α: 1.67, ddd (12.6, 9.0, 1.2) |
| 12 | 1.21, s | 1.16, s | 0.91, s | 0.92, s |
| 13 | 1.06, d (7.2) | 1.06, d (7.2) | 1.08, d (7.2) | 1.00, d (7.2) |
| 14 | 1.15, s | 1.08, s | 1.11, s | 1.08, s |
| 15 | 1.12, s | 1.03, s | 1.20, s | 1.19, s |
| 4-OH | 2.15, brs | 4.17, brs | ||
| 6-OH | 2.53, brs | 4.07, brs | ||
| 8-OH | 1.98, brs | 3.93, brs | ||
a Measured at 400 MHz; b Measured at 600 MHz.