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. 2016 Sep 2;14(9):160. doi: 10.3390/md14090160

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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I.t. administration of 11-dehydrosinulariolide improved locomotor recovery in rats with SCI. After SCI, locomotor behavior was evaluated using the BBB score every 3 days. Significant improvement was observed in hindlimb motor function with 1 and 5 μg 11-dehydrosinulariolide-treated rats after SCI (A). The area under the BBB score-time curve for 1 and 5 μg 11-dehydrosinulariolide-treated rats indicated significant improvements compared with those administered the vehicle (B). Data are expressed as means ± SEMs; * p < 0.05 compared with the vehicle group.