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. 2016 Sep 2;14(9):160. doi: 10.3390/md14090160

Figure 3.

Figure 3

11-Dehydrosinulariolide enhanced the SCI-induced activation of cell survival-related signaling proteins, Akt and ERK. The rats were sacrificed 8 h after SCI, and their spinal cords were harvested to perform immunoblotting (AC) and immunohistochemistry (DF). 11-Dehydrosinulariolide (i.t.) significantly enhanced the SCI-induced activation of neuronal Akt, ERK, and CREB. Data are expressed as means ± SEMs; # p < 0.05 and ## p < 0.001 compared with the control group; * p < 0.05 and ** p < 0.001 compared with the vehicle group. Scale bars = 50 μm.