Figure 1.

Nrf2-activators dose-dependently increase antioxidant protein expression in OLN-93 cells. HO-1 (A), NQO-1 (B) and p62 (C) protein expression levels after 24 h treatment in the OLN-93 oligodendrocyte cell line with 5 µM or 10 µM SFN, 45 µM or 90 µM MMF, 30 µg/mL or 60 µg/mL Protandim or their respective DMSO or EtOH vehicle control. Protein levels were assayed by Western blotting. Data are presented as percentage of control and expressed as the mean ± SEM of 3 independent experiments. All statistics reflect one-way ANOVA tests with post hoc Bonferroni correction; * p < 0.05, ** p < 0.01; *** p < 0.001.