Figure 4.
Protandim increases total glutathione levels in mature primary rat OLs. Mature primary rat OLs differentiated for 7 days were treated for 24 h with 5 µM SFN, 90 µM MMF,30 µg/mL Protandim or their respective DMSO or EtOH control. Total glutathione levels were assayed using the GSH-Glo kit from Promega. Data are presented as percentage of control and expressed as the mean ± SEM of 3 independent experiments. Statistics reflect one-way ANOVA test with post hoc Bonferroni correction; *** p < 0.001.