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. 2016 Sep 28;6:34333. doi: 10.1038/srep34333

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Copyright © 2016, The Author(s)

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Conserved residues are indicated with filled circles while identical residues are highlighted with an asterisk. Residues highlighted in grey boxes are those previously established to confer sensitivity of Na_V1.7 to the gating modifier peptide HwTx-IV. Conserved residues that have been shown to confer sensitivity of VSD_K or Na_V1.7 to gating modifier peptides are highlighted in red.