Table 4. Altered cellular morphology and function pathways in adult F1 mice treated with caffeine during E6.5–10.5.
| p-value | Activation z-scorea | # of molecules | |
|---|---|---|---|
| Cell death and survival | |||
| Cytolysis | 6.79E-04 | −1.034 | 7 |
| Proliferation of cells | 2.11E-03 | −0.513 | 37 |
| Cell death | 2.40E-03 | −0.323 | 34 |
| Cell morphology, cellular function and maintenance | |||
| Nucleation of filaments | 9.91E-04 | — | 3 |
| Cellular homeostasis | 3.38E-03 | 0.297 | 19 |
| Morphology of cells | 5.15E-03 | — | 22 |
| Generation of filaments | 6.22E-03 | — | 2 |
| Cell signaling | |||
| Activation of cells | 2.76E-05 | −0.500 | 18 |
| Quantity of Ca2+ | 8.31E-03 | −0.240 | 7 |
aA positive z-score means the pathway is activated, and a negative z-score indicates the pathway is inhibited.