Figure 1. Transcriptional regulation in intestinal epithelial Caco-2 cells infected with Campylobacter concisus.

(A) Number of significantly differentially expressed transcripts following infection with C. concisus BAA-1457 or UNSWCD. (B) Comparison of the responses of Caco-2 cells to C. concisus BAA-1457 (outer circle) and UNSWCD (inner circle). Transcripts were mapped according to location on human chromosomes. Responses were visualised using circular Circos plot, with transcripts increased in expression in red and those decreased in blue. (C) Numbers of upregulated (red) and downregulated (green) transcripts visualised in the outer circles, and types of regulated transcripts visualised independently in the inner circles.