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. 2016 Sep 28;6:34111. doi: 10.1038/srep34111

Figure 7. Exercise protects against METH-induced inflammatory cytokines in plasma.

Figure 7

Mice were exposed to METH as in Fig. 1, followed by a 2 week exercise or sedentary regimen. Plasma IL-1β (a) and TNF-α (b) levels were measured by multiplex cytokine bead-based ELISA. First blood collection was performed 24 h post chronic METH or vehicle treatment and the second after the subsequent 2 weeks of exercise or sedentary housing. *p < 0.05 and **p < 0.01 (n = 6 per group). Protein levels of IL-1β (c) and TNF-α (d) in the hippocampal homogenates were measured as in (a and b). mRNA levels of TNFα (e) and BDNF (f) in the dissected hippocampi as measured by qPCR with mouse-specific primers and probes (n = 5 per group).