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. 2016 Sep 28;6:34022. doi: 10.1038/srep34022

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Two different types of FAIM2 antibodies detecting N-terminus (FAIM2-abN) and C-terminus (FAIM2-abC) were used for FAIM2 IHC analysis. Antibody specific to synaptophysin, a known NE tumor marker, was used for parallel direct comparison. While SCLC sections with two different FAIM2 antibodies showed moderate to strong FAIM2 expression, no detectable or less intense synaptophysin expression was observed in the adjacent SCLC sections, suggesting that FAIM2 may outperform synaptophysin as a diagnostic marker of SCLC.