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. 2016 Sep 28;6:34164. doi: 10.1038/srep34164

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Bar graph shows the number of genes mapping to each of the 10 most statistically significant GO terms to which the 380 up-regulated genes enriched. Line represents the −log(p-value) associated with each GO term (b) Heat map of the genes that mapped to the GO process “response to virus” grouped by function (PRR = pathogen recognition receptor; TF = transcription factor; ISG = immune stimulated gene). (c) Bar graph shows the number of genes mapping to each of the 10 most statistically significant disease pathways to which 400 down-regulated genes enriched. Line represents the −log(p-value) associated with each GO term. (d) Heat map of the DEGs with a FC >8 that enriched to “respiratory tract diseases” and “lung diseases”.