Title |
• Should identify as systematic review and/or meta-analysis |
Introduction |
• Clearly states the objective and rationale for the review, according to PICOTS layout |
• Clear clinical question to address stated |
Methods |
• Defines important key terms e.g., “minimally invasive” |
• Primary and secondary outcomes described |
• States which electronic databases were used |
• States year range for literature search |
• States/summarizes the search strategy used, based on PICOTS |
• States inclusion and exclusion criteria |
• States how to deal with abstracts, conference reports, editorials, duplicates studies etc. |
• States the reviewers (should be 2 or more) performing the literature search |
• Statistical methodology described |
• Publication bias assessment and heterogeneity analysis described |
• Defining “clinical relevance” of outcome, e.g., 30% improvement in pain score as clinically relevant |
Results |
• Provides information on PRISMA search strategy workflow e.g. number of studies screened, and numbers of studies finally included |
• Study characteristics presented (usually in tabular form), including year, study enrolment, level of evidence, design, country, demographics, operative parameters, complications, functional outcomes and radiographic outcomes |
• Intra-study risk of bias assessment |
• Inter-study risk of bias assessment |
• Quality appraisal of included studies |
• Summary table for outcomes of individual studies |
• Descriptions of meta-analysis and heterogeneity analysis results in words |
• Additional analysis should also be described |
Discussion |
• Main findings summarized |
• Key limitations and strengths discussed |
• Overall general interpretation and future directions of research discussed |
• Conclusions should be appropriate according to the data presented |
Funding |
• Funding, acknowledgements, and conflicts of interest mentioned |
Figures |
• PRISMA flow-chart for search strategy |
• Forest plots of primary and secondary outcomes |
• Funnel plot for publication bias |
• Trim-and-fill analysis plots |
• Subgroup analysis forest plots/meta-regression graphs for heterogeneity assessment if appropriate |
Supplementary Tables |
• Search strategy for at least one database |
• GRADE approach for assessment of outcomes |
• Checklist for quality appraisal, e.g., Furlan, Cowley, Newcastle-Ottawa assessment scale |
• PRISMA checklist, abbreviation not previously touched on checklist |