Table 4.
Method | γa | σb | P-valuec |
---|---|---|---|
I-Mutent3.0 | 0.12 | 2.04 | 3.7E-4 |
INPS | 0.27 | 1.96 | 7.9E-4 |
mCSM | 0.18 | 2.09 | 7.0E-2 |
STRUM | 0.40 | 1.91 |
aγ, PCC between predicted and experiment
aσ, RMSE of prediction in Kcal/mol.
aP-value, P-value in Wilcoxon test between the RMSE of STRUM and that by the control methods on the mutations.