Table 2.

Predictors of MACE

	Univariate		Multivariate*
	HR (95% CI)	p-value	HR (95% CI)	p-value
Age	1.04 (1.03-1.05)	<0.001	1.03 (1.02-1.04)	<0.001
Female gender	0.97 (0.84-1.12)	0.68
Hypertension	1.51 (1.31-1.75)	<0.001	1.24 (1.02-1.51)	0.035
Hyperlipidemia	0.93 (0.81-1.07)	0.32
Diabetes	1.92 (1.64-2.25)	<0.001	1.42 (1.16-1.74)	0.001
Smoking	1.20 (1.03-1.41)	0.03	1.48 (1.21-1.82)	<0.001
Family History	0.90 (0.77-1.06)	0.21
Typical Angina	1.52 (1.25-1.85)	<0.001	1.30 (1.01-1.66)	0.038
Atypical Angina	0.98 (0.83-1.16)	0.82	0.99 (0.79-1.24)	0.904
Noncardiac Chest Pain	0.84 (0.67-1.05)	0.12	1.12 (0.85-1.66)	0.396
Dyspnea	1.50 (1.22-1.84)	<0.001
Aspirin	1.63 (1.37-1.94)	<0.001
Beta blocker	1.25 (1.04-1.50)	0.02
ACE/ARB	1.58 (1.32-1.88)	<0.001	1.26 (1.04-1.52)	0.017
Statin	1.36 (1.14-1.62)	<0.001
Non-obstructive disease	0.95 (0.81-1.10)	0.47	2.25 (1.66-3.05)	<0.001
1-vessel obstructive disease	1.65 (1.40-1.93)	<0.001	2.86 (2.08-3.94)	<0.001
2-vessel obstructive disease	1.73 (1.41-2.11)	<0.001	3.46 (2.44-4.91)	<0.001
3-vessel obstructive disease	2.42 (1.99-2.95)	<0.001	4.68 (3.31-6.61)	<0.001
Early revascularization	2.41 (2.07-2.80)	<0.001

^*Hazard ratios shown only for variables retained.