TABLE 1 .

Summary statistics for the genetic recombination events identified in each serotype

Serotype	Sequence cluster (SC)	No. of isolates (n)	Mean no. of recombination events/isolate (μre)	Mean recombination to mutation (μr/m)		Recombination size (bp)		Pherotypea
				Mean	95% CIb	Mean	95% CI	CSP1	CSP2	Other
5	SC1	25	2	2.82	0.29−5.35	7,642	3,877−11,407	100	0	0
1	SC2	83	0.73	2.61	0.74−4.48	8,727	5,753−11,702	98.78	0	1.22
6A	SC3	11	8.91	23.45	1.54−45.44	11,579	8,872−14,286	0	100	0
19A	SC4	12	5.58	11.26	4.64−17.89	9,143	6,308−11,979	0	0	100
16F	SC5	9	0.11	0.44	0−1.39	36,616	0	0	0	100
3	SC6	10	8.1	9.45	0−23.53	8,020	6,201−9,839	0	0	100
10B	SC7	14	2.07	4.15	0−8.70	9,855	4,805−14,905	76.47	17.65	5.88
23F	SC8	19	12.26	12.53	7.33−17.72	8,094	6,737−9,451	94.74	0	5.26
35B	SC9	13	20.08	17.02	5.31−28.74	9,022	7,987−10,056	100	0	0
6A	SC9	12	11.92	12.85	4.55−21.15	7,115	5,697−8,532	100	0	0
12F	SC10	19	5.16	8.17	2.38−13.97	7,709	6,016−9,401	94.74	0	5.26
7A/F	SC11	20	6.4	8.74	3.09−14.38	6,924	5,547−8,302	95	0	5
14	SC12	15	4	13.93	4.70−23.16	6,745	4,926−8,563	100	0	0
18B/C	SC13	8	6.67	3.49	0−11.15	9,469	6,215−12,724	83.78	16.22	0
4	SC13	6	0.75	1.67	0−3.67	9,208	0−20,175	38.75	32.56	28.29

^aProportion of the pneumococcal pherotypes or competence-stimulating peptide (CSP) encoded by the comC gene and its variants in each SC. Detailed information about the CSPs is shown in Fig. S2c and S2d in the supplemental material.

^b95% CI, 95% confidence interval.