Table 1.
Interactomes and the datasets used to reverse engineer them
| Dataset | Interactome | |||||
|---|---|---|---|---|---|---|
| Tissue type | Samples | Platform | Reference | Regulator | Targets | Interactions |
| B-cell | 254 | HG-U95Av2 | 24 | 633(TFs) | 6,403 | 173,539 |
| B-cell | 264 | HG-U133plus2 | 34 | 1,223(TFs) | 13,007 | 327,837 |
| Glioblastoma | 176 | HG-U133A | 48 | 835(TFs) | 8,263 | 256,965 |
| Bladder carcinoma | 241 | RNAseq | TCGA | 1,813(TFs) | 20,006 | 245,871 |
| 666(coTFs) | 18,739 | 181,730 | ||||
| 3,455(Sig) | 20,441 | 317,127 | ||||
| Breast carcinoma | 1,037 | RNAseq | TCGA | 1,813(TFs) | 20,428 | 249,501 |
| 666(coTFs) | 20,220 | 217,916 | ||||
| 3,455(Sig) | 20,515 | 366,924 | ||||
| Colon adenocarcinoma | 434 | RNAseq | TCGA | 1,813(TFs) | 20,462 | 294,725 |
| 666(coTFs) | 19,742 | 204,682 | ||||
| 3,456(Sig) | 20,492 | 369,870 | ||||
| Head and neck squamous cell carcinoma | 424 | RNAseq | TCGA | 1,813(TFs) | 20,452 | 319,799 |
| 666(coTFs) | 19,874 | 212,214 | ||||
| 3,456(Sig) | 20,520 | 395,966 | ||||
| Kidney renal clear cell carcinoma | 506 | RNAseq | TCGA | 1,813(TFs) | 20,474 | 355,932 |
| 666(coTFs) | 20,080 | 259,151 | ||||
| 3,456(Sig) | 20,522 | 429,651 | ||||
| Lung adenocarcinoma | 488 | RNAseq | TCGA | 1,813(TFs) | 20,405 | 341,285 |
| 666(coTFs) | 19,832 | 214,048 | ||||
| 3,456(Sig) | 20,528 | 472,933 | ||||
| Lung squamous cell carcinoma | 482 | RNAseq | TCGA | 1,813(TFs) | 20,426 | 342,737 |
| 666(coTFs) | 19,948 | 221,178 | ||||
| 3,453(Sig) | 20,498 | 397,774 | ||||
| Ovarian serous cystadenocarcinoma | 262 | RNAseq | TCGA | 1,813(TFs) | 20,261 | 247,063 |
| 666(coTFs) | 19,082 | 150,949 | ||||
| 3,456(Sig) | 20,459 | 334,906 | ||||
| Prostate adenocarcinoma | 297 | RNAseq | TCGA | 1,813(TFs) | 20,215 | 228,977 |
| 666(coTFs) | 19,599 | 180,315 | ||||
| 3,456(Sig) | 20,466 | 315,155 | ||||
| Rectum adenocarcinoma | 163 | RNAseq | TCGA | 1,810(TFs) | 18,506 | 236,899 |
| 666(coTFs) | 16,939 | 173,579 | ||||
| 3,455(Sig) | 19,773 | 332,088 | ||||
| Stomach adenocarcinoma | 238 | RNAseq | TCGA | 1,808(TFs) | 22,017 | 267,138 |
| 661(coTFs) | 20,984 | 194,782 | ||||
| 3,442(Sig) | 22,458 | 438,054 | ||||
| Thyroid carcinoma | 498 | RNAseq | TCGA | 1,813(TFs) | 20,478 | 333,725 |
| 666(coTFs) | 20,038 | 225,544 | ||||
| 3,369(sig) | 20,511 | 408,356 | ||||
| Uterine corpus endometrial carcinoma | 517 | RNAseq | TCGA | 1,813(TFs) | 20,471 | 350,994 |
| 666(coTFs) | 20,190 | 237,518 | ||||
| 3,456(Sig) | 20,527 | 501,212 | ||||
| Glioblastoma multiforme | 154 | RNAseq | TCGA | 1,811(TFs) | 18,354 | 259,025 |
| 660(coTFs) | 16,655 | 157,230 | ||||
| 3,455(Sig) | 19,616 | 393,595 | ||||
| Low grade glioma | 370 | RNAseq | TCGA | 1,813(TFs) | 20,357 | 328,373 |
| 666(coTFs) | 19,558 | 228,634 | ||||
| 3,455(Sig) | 20,463 | 372,802 | ||||
| Skin cutaneous melanoma | 374 | RNAseq | TCGA | 1,813(TFs) | 20,475 | 281,486 |
| 666(coTFs) | 19,656 | 177,388 | ||||
| 3,453(Sig) | 20,501 | 418,136 | ||||
| Sarcoma | 105 | RNAseq | TCGA | 1,715(TFs) | 14,262 | 142,041 |
| 620(coTFs) | 10,920 | 72,486 | ||||
| 3,024(Sig) | 15,552 | 177,063 | ||||