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Risk of breast cancer as estimated by mtDNA index.
| mtDNA index (relative copy number) | Number of cases (%) | Number of controls (%) | OR (95% CI) a |
|---|---|---|---|
| Continuous variable | 103 (100) | 103 (100) | 3.54 (1.94–6.46) |
| By tertiles | |||
| ≤0.64 | 10 (9.7) | 33 (32) | 1.00 |
| 0.65–1.18 | 34 (33) | 36 (35) | 3.29 (1.40–7.74) |
| ≥1.19 | 59 (57.3) | 34 (33) | 6.40 (2.74–14.94) P for trend < 0.01 |
| Median | |||
| <0.80 | 19 (18.4) | 51 (49.5) | 1.00 (reference) |
| ≥0.80 | 84 (81.6) | 52 (50.5) | 4.67 (2.45–8.92) |
Odds ratio was adjusted by age only.
