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. 2016 Sep 24;22:3394–3408. doi: 10.12659/MSM.900783

Table 3.

The enriched Gene Ontology and pathway terms of differentially expressed lncRNAs in the mild pneumonia compared with the controls.

Category of lncRNAs Category of functional terms ID Term Gene count FDR
Upregulated GO-BP GO: 0008150 Biological_process 469 3.46E-22
GO-BP GO: 0009987 Cellular process 434 8.85E-12
GO-BP GO: 0050896 Response to stimulus 261 0.0004501
GO-BP GO: 0050794 Regulation of cellular process 303 0.003139471
GO-BP GO: 0044699 Single-organism process 378 0.004578225
GO-CC GO: 0005575 Cellular_component 510 2.68E-09
GO-MF GO: 0003674 Molecular_function 481 1.52E-22
GO-MF GO: 0005488 Binding 399 0.002334936
GO-MF GO: 0060089 Molecular transducer activity 74 0.016441823
Downregulated GO-BP GO: 0008150 Biological_process 1852 2.03E-100
GO-BP GO: 0009987 Cellular process 1685 8.04E-41
GO-BP GO: 0044699 Single-organism process 1517 2.59E-23
GO-BP GO: 0044763 Single-organism cellular process 1386 2.07E-18
GO-BP GO: 0008152 Metabolic process 1337 4.59E-18
GO-CC GO: 0005575 Cellular_component 1965 2.83E-43
GO-CC GO: 0005623 Cell 1758 1.73E-08
GO-CC GO: 0044464 Cell part 1753 2.42E-08
GO-CC GO: 0005622 Intracellular 1546 9.50E-07
GO-CC GO: 0044424 Intracellular part 1504 1.05E-05
GO-MF GO: 0003674 Molecular_function 1849 1.12E-96
GO-MF GO: 0005488 Binding 1554 3.18E-22
GO-MF GO: 0005515 Protein binding 1174 6.27E-10
GO-MF GO: 0003824 Catalytic activity 675 6.37E-10
GO-MF GO: 0016740 Transferase activity 292 9.63E-07
KEGG hsa03010 Ribosome 32 0.009558616

LncRNA – long non-coding RNA; GO – Gene Ontology; MF – molecular function; CC – cellular component; BP – biological process; FDR – false discovery rate.