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. 2016 Sep 28;10(9):e0005013. doi: 10.1371/journal.pntd.0005013

Table 2. CC20s of FQs against DNA gyrases of WT and mutant M. leprae.

Drug CC20 (μg/mL)
WT Gly89Cys Ala91Val Asp95Gly
DC-159a 0.1 ± 0.0 0.8 ± 0.1 0.4 ± 0.1 1.4 ± 0.3
Sitafloxacin 0.1 ± 0.0 1.1 ± 0.3 0.4 ± 0.1 1.3 ± 0.4
Moxifloxacin 0.4 ± 0.0 10.8 ± 2.2 2.2 ± 0.4 11.6 ± 1.9