Table 4.
Single nucleotide substitutions identified by pair-wise comparison between the contigs of six Taiwan M. tuberculosis strains (this study) and the genomes of four completed M. tuberculosis strains (NCBI).
| REFERENCES | NUMBER (%) OF SYNONYMOUS DIFFERENCES | NUMBER (%) OF NON-SYNONYMOUS DIFFERENCES | NON-SYN/SYN | |
|---|---|---|---|---|
| H37Rv | M3 (Haarlem) | 306 (41.2) | 437 (58.8) | 1.428 |
| M7 (LAM3) | 307 (40.3) | 455 (59.7) | 1.482 | |
| W6 (Beijing) | 445 (39.5) | 682 (60.5) | 1.533 | |
| A18 (EAI) | 681 (38.3) | 1096 (61.7) | 1.609 | |
| A27 (T1) | 324 (41.3) | 460 (58.7) | 1.420 | |
| M24 (Beijing) | 489 (39.4) | 753 (60.6) | 1.540 | |
| CDC1551 | M3 (Haarlem) | 368 (40.2) | 547 (59.8) | 1.468 |
| M7 (LAM3) | 387 (41.5) | 546 (58.5) | 1.411 | |
| W6 (Beijing) | 412 (36.7) | 711 (63.3) | 1.726 | |
| A18 (EAI) | 672 (37.6) | 1116 (62.4) | 1.661 | |
| A27 (T1) | 363 (40.3) | 538 (59.7) | 1.482 | |
| M24 (Beijing) | 486 (39.2) | 754 (60.8) | 1.551 | |
| F11 | M3 (Haarlem) | 259 (39.6) | 396 (60.4) | 1.529 |
| M7 (LAM3) | 58 (50.4) | 57 (49.6) | 0.982 | |
| W6 (Beijing) | 419 (39.4) | 644 (60.6) | 1.537 | |
| A18 (EAI) | 657 (38.6) | 1047 (61.4) | 1.594 | |
| A27 (T1) | 282 (40.7) | 409 (59.3) | 1.450 | |
| M24 (Beijing) | 417 (37.9) | 684 (62.1) | 1.640 | |
| H37Ra | M3 (Haarlem) | 287 (41.5) | 404 (58.5) | 1.408 |
| M7 (LAM3) | 292 (40.7) | 425 (59.3) | 1.455 | |
| W6 (Beijing) | 424 (39.1) | 660 (60.9) | 1.557 | |
| A18 (EAI) | 670 (38.5) | 1069 (61.5) | 1.596 | |
| A27 (T1) | 303 (41.7) | 423 (58.3) | 1.396 | |
| M24 (Beijing) | 458 (38.7) | 724 (61.3) | 1.581 |