Table 1. Baseline Demographics and Clinical Characteristics of Patients.
| Characteristics | Total | DCV/ASV | LDV/SOF | P-value† |
|---|---|---|---|---|
| (n = 100) | (n = 24) | (n = 76) | ||
| Age, year | 71.0 (63.5, 76.0) | 76.0 (69.0, 80.0) | 69.0 (63.0, 75.0) | <0.01 |
| Sex, Male, n(%) | 39 (39.0) | 8 (33.3) | 31 (40.8) | 0.51 |
| BMI (kg/m2) | 22.9 (21.0, 25.0) | 23.1 (20.9, 25.9) | 22.9 (21.0, 24.8) | 0.54 |
| Fib-4 index, 3.25≦, n (%) | 70 (70.0) | 19 (79.2) | 51 (67.1) | 0.26 |
| HCV-RNA (log10IU/ml) | 6.0 (5.6, 6.4) | 6.1 (5.4, 6.4) | 6.0 (5.6, 6.4) | 0.64 |
| HCV core antigen (log10(fmol/L)) | 3.6 (3.3, 4.0) | 3.5 (3.2, 3.9) | 3.6 (3.3, 4.0) | 0.40 |
| AST (IU/L) | 49.0 (35.0, 64.5) | 49.0 (34.5, 67.5) | 49.0 (35.5, 63.0) | 0.91 |
| ALT (IU/L) | 38.0 (26.0, 55.0) | 36.0 (18.0, 57.0) | 38.0 (28.0, 53.5) | 0.15 |
| γ-GTP (IU/L) | 29.5 (20.0, 42.5) | 29.5 (19.5, 44.0) | 29.5 (20.5, 42.0) | 0.97 |
| Alb (g/dl) | 3.9 (3.5, 4.3) | 3.9 (3.5, 4.2) | 3.9 (3.5, 4.4) | 0.70 |
| Platelet count (×103/μl) | 125 (90, 153) | 122 (94, 144) | 126 (90, 157) | 0.86 |
| TC (mg/dl) | 155.5 (131.5, 185.0) | 149.0 (133.0, 168.0) | 157.5 (131.0, 186.0) | 0.48 |
| LDL-C (mg/dl) | 84.5 (68.4, 103.9) | 80.2 (65.3, 94.6) | 87.5 (68.6, 105.8) | 0.28 |
| TG (mg/dl) | 96.0 (69.5, 128.3) | 86.0 (61.5, 110.5) | 98.0 (71.3, 143.0) | 0.08 |
| AFP (ng/ml) | 6.0 (4.0, 11.5) | 6.1 (5.4, 6.4) | 5.0 (4.0, 11.0) | 0.07 |
Continuous variables are shown as median (with IQR) with analysis by Mann-Whitney’s test.
Categorical variables are expressed as number of patients (n) with frequencies (%), with analysis by Chi-squared test.
†DCV/ASV v.s LDV/SOF