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. 2016 Sep 28;11(9):e0157237. doi: 10.1371/journal.pone.0157237

Table 1. List of top 50 genes up-regulated in heat stressed buffalo MECs (Fold change > = 3.0).

Fold change > = 3.0 (Relative to control)
S.No. Gene_ID GeneSymbol 30m 2h 4h 8h 12h 16h 24h Description
1 A_73_P108026 BOLA 8.503 8.157 5.418 5.151 5.126 6.863 5.343 MHC class I heavy chain
2 A_73_P046761 MRPL55 7.623 7.325 7.567 7.213 6.975 7.573 7.242 mitochondrial ribosomal protein L55
3 A_73_118246 PFKFB3 7.231 6.506 3.138 2.763 2.697 4.123 2.861 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
4 A_73_115573 PSMC2 6.850 6.499 6.759 6.945 6.670 6.487 6.767 proteasome (prosome, macropain) 26S subunit, ATPase, 2
5 A_73_118860 ENDOD1 6.156 5.320 5.808 5.828 5.418 6.397 5.988 endonuclease domain containing 1
6 A_73_P030366 ARID5A 6.093 5.457 3.085 3.198 3.136 3.609 3.246 AT rich interactive domain 5A (MRF1-like)
7 A_73_107649 HBXIP 5.747 5.238 4.405 4.628 4.357 4.158 4.325 hepatitis B virus x interacting protein
8 A_73_105502 SENP3 5.182 5.123 5.028 4.684 4.480 4.812 4.548 SUMO1/sentrin/SMT3 specific peptidase 3
9 A_73_P046036 PIM1 4.940 5.002 4.043 3.629 3.351 3.923 3.976 pim-1 oncogene
10 A_73_P046636 TAX1BP3 4.892 4.737 4.906 5.161 5.353 5.225 5.545 Tax1 (human T-cell leukemia virus type I) binding protein 3
11 A_73_P324666 HSPB8 4.451 4.825 4.994 5.311 2.946 4.265 1.281 heat shock 22kDa protein 8
12 A_73_P041676 ATP6V1H 4.440 3.846 3.855 4.248 4.467 4.079 4.597 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
13 A_73_102559 GDI1 4.427 4.031 3.974 2.945 3.437 4.001 4.085 GDP dissociation inhibitor 1
14 A_73_P421171 C29H11orf68 4.322 4.090 4.481 4.703 4.721 4.610 4.351 chromosome 29 open reading frame, human C11orf68
15 A_73_P334111 NAGA 4.252 3.422 2.778 3.199 2.989 2.996 3.279 N-acetylgalactosaminidase, alpha-
16 A_73_P370971 NCAPH2 4.126 3.587 3.700 3.123 3.623 3.595 3.993 non-SMC condensin II complex, subunit H2
17 A_73_P051671 FAM104A 4.045 3.852 3.630 4.018 3.967 3.489 3.572 family with sequence similarity 104, member A
18 A_73_108441 HRSP12 4.006 3.732 1.963 2.461 2.214 2.333 2.194 heat-responsive protein 12
19 A_73_P394126 CSRNP1 3.995 4.445 1.252 1.733 1.822 1.616 1.314 cysteine-serine-rich nuclear protein 1
20 A_73_121151 SACM1L 3.968 3.250 3.338 3.232 3.232 3.234 3.238 SAC1 suppressor of actin mutations 1-like (yeast)
21 A_73_109582 MTF2 3.903 2.984 3.064 4.861 4.205 2.929 4.034 metal response element binding transcription factor 2
22 A_73_P325281 G3BP1 3.896 3.407 3.788 3.955 3.869 3.619 3.718 GTPase activating protein (SH3 domain) binding protein 1
23 A_73_116684 ARMC6 3.891 3.610 4.225 4.358 4.588 4.281 4.255 armadillo repeat containing 6
24 A_73_P465393 DNAJB2 3.886 3.021 3.424 4.185 4.034 3.189 3.812 DnaJ (Hsp40) homolog, subfamily B, member 2
25 A_73_114308 CDC42EP2 3.807 3.370 3.853 3.629 3.220 4.454 3.028 CDC42 effector protein (Rho GTPase binding) 2
26 A_73_P441761 PMM1 3.774 3.618 4.138 3.406 3.664 3.921 3.817 phosphomannomutase 1
27 A_73_P035201 BRI3 3.734 3.626 3.459 4.010 3.482 3.248 2.986 brain protein I3
28 A_73_P258001 KIAA0020 3.684 3.429 3.501 4.332 3.937 3.381 3.972 KIAA0020
29 A_73_P383651 SQSTM1 3.600 3.672 3.778 4.253 4.391 4.223 3.930 sequestosome 1
30 A_73_P106906 PTPN6 3.580 3.263 1.726 1.969 2.296 1.859 2.212 protein tyrosine phosphatase, non-receptor type 6
31 A_73_108508 CD320 3.565 3.298 4.017 3.296 3.240 3.701 3.206 CD320 molecule
32 A_73_120943 DLGAP4 3.528 2.980 2.628 2.991 3.206 2.823 3.572 discs, large (Drosophila) homolog-associated protein 4
33 A_73_P080981 FAM46A 3.512 3.153 4.728 3.184 2.735 4.460 2.181 family with sequence similarity 46, member A
34 A_73_P510368 SLC26A11 3.336 2.865 2.148 2.487 2.241 2.705 2.251 solute carrier family 26, member 11
35 A_73_100950 IL20RA 3.290 2.940 3.922 2.732 2.767 4.177 3.033 interleukin 20 receptor, alpha
36 A_73_P044846 CNP 3.278 2.988 3.071 2.797 2.828 3.061 2.739 2',3'-cyclic nucleotide 3' phosphodiesterase
37 A_73_107984 TXNDC17 3.266 2.872 3.259 3.667 3.378 3.248 3.421 thioredoxin domain containing 17
38 A_73_104610 TSPO 3.243 2.926 2.940 3.441 3.090 3.670 3.348 translocator protein (18kDa)
39 A_73_101196 RSPRY1 3.234 2.466 1.904 1.903 1.965 1.827 1.874 ring finger and SPRY domain containing 1
40 A_73_106773 KLHDC10 3.224 3.313 3.961 3.515 3.466 3.695 3.042 kelch domain containing 10
41 A_73_102546 SCOC 3.211 3.102 3.385 3.613 3.563 3.260 3.552 short coiled-coil protein
42 A_73_105407 C16H1orf27 3.181 2.925 3.383 3.622 3.585 2.863 3.651 chromosome 16 open reading frame, human C1orf27
43 A_73_P080636 POMT2 3.167 2.657 2.707 2.580 2.336 2.490 2.655 protein-O-mannosyltransferase 2
44 A_73_P034946 SOX4 3.154 3.249 3.356 3.831 4.043 3.737 3.875 SRY (sex determining region Y)-box 4
45 A_73_111382 ZBTB48 3.151 2.648 2.856 2.852 3.125 3.065 2.991 zinc finger and BTB domain containing 48
46 A_73_P340001 MRPS12 3.107 2.614 3.130 2.509 2.838 3.089 3.084 mitochondrial ribosomal protein S12
47 A_73_P040866 SEC61A1 3.085 2.690 2.960 3.435 3.237 2.602 2.968 Sec61 alpha 1 subunit (S. cerevisiae)
48 A_73_120765 CNPY4 3.072 2.987 3.456 3.439 3.034 3.346 3.293 canopy 4 homolog (zebrafish)
49 A_73_115031 GPR137 3.004 2.341 2.488 2.817 2.988 3.002 2.516 G protein-coupled receptor 137
50 A_73_P271701 FUS 2.942 2.768 3.031 2.788 2.501 2.463 2.505 fused in sarcoma