Table 3. List of genes classified in major functional categories during post heat stress (relative to control) in buffalo MECs.

Heat shock protein family		Fold change > = 3.0 (Relative to control)
Gene_ID	GeneSymbol	30 m	2 h	4 h	8 h	12 h	16h	24 h	Description
A_73_P092016	HSPA6	5.08	1.57	-1.52	6.14	2.90	0.07	0.43	heat shock 70kDa protein 6 (HSP70B')
A_73_P324666	HSPB8	4.45	4.83	4.99	5.31	2.95	4.27	1.28	heat shock 22kDa protein 8
A_73_P465393	DNAJB2	3.89	3.02	3.42	4.18	4.03	3.19	3.81	DnaJ (Hsp40) homolog, subfamily B, member 2
A_73_P474283	HSPA1A	3.21	2.64	1.54	4.80	2.84	0.41	-1.35	heat shock 70kDa protein 1A
A_73_P262981	DNAJB1	1.60	0.12	0.47	1.73	-0.07	0.25	-0.65	DnaJ (Hsp40) homolog, subfamily B, member 1
A_73_110555	HSPH1	1.49	1.34	0.73	2.86	1.03	-1.24	-0.01	heat shock 105kDa/110kDa protein 1
A_73_P038581	HSPA5	1.39	0.84	1.15	1.75	0.44	-0.15	-1.43	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Apoptotic gene family
A_73_P108956	BCL2	3.32	2.88	-0.58	-2.11	-2.57	1.26	-0.69	B-cell CLL/lymphoma 2
A_73_100589	IRF5	3.00	2.50	0.25	0.16	0.21	0.86	0.19	interferon regulatory factor 5
A_73_P033666	BCL2L14	2.53	2.24	-0.05	-0.19	-0.79	0.89	0.43	BCL2-like 14 (apoptosis facilitator)
A_73_120639	BCL2L11	2.39	1.96	-0.05	-0.03	0.48	-0.60	0.06	BCL2-like 11 (apoptosis facilitator)
A_73_P087306	NFKB1	2.22	2.59	-0.58	-0.47	-0.15	-0.98	-0.11	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
A_73_P047636	NFKBIE	2.18	2.04	-0.70	-0.44	-0.18	-0.20	-0.22	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
A_73_105509	PIK3R1	1.68	0.58	0.03	-0.19	0.14	0.68	0.43	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
A_73_P059646	IRF2	1.65	1.64	1.01	-0.57	-0.42	-1.25	-0.89	interferon regulatory factor 2
A_73_P271841	MCL1	1.33	1.47	-0.67	-0.46	-0.47	-0.27	-0.73	myeloid cell leukemia sequence 1 (BCL2-related)
A_73_104047	CFLAR	1.11	1.85	-1.52	-0.19	0.04	0.07	0.43	CASP8 and FADD-like apoptosis regulator
Immune system genes
A_73_P108026	BOLA	8.50	8.16	5.42	5.15	5.13	6.86	5.34	MHC class I heavy chain
A_73_110556	IL1B	8.33	7.56	-1.30	0.34	0.01	0.12	0.64	interleukin 1, beta
A_73_P038356	BOLA-DRA	7.62	6.75	3.38	7.57	-0.66	5.14	0.09	major histocompatibility complex, class II, DR alpha
A_73_P048896	TNF	7.58	7.47	-1.52	-0.19	-0.79	0.07	0.43	tumor necrosis factor
A_73_P108101	IL1A	7.36	6.88	0.45	-0.19	-0.72	0.07	0.43	interleukin 1, alpha
A_73_P031501	CXCL2	4.15	3.66	0.97	-0.19	0.96	0.07	0.43	chemokine (C-X-C motif) ligand 2
A_73_P030396	IL10	3.44	1.99	-1.82	0.20	0.14	-0.92	0.00	interleukin 10
A_73_P035281	BOLA-N	2.46	3.58	-0.30	-0.35	-0.26	1.44	-0.60	MHC class I antigen
A_73_P087306	NFKB1	2.22	2.59	-0.58	-0.47	-0.15	-0.98	-0.11	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
A_73_P048171	IL6	2.07	1.49	-1.52	-0.19	-0.79	0.07	0.43	interleukin 6 (interferon, beta 2)
A_73_110221	IL13	-1.05	-1.86	-1.59	0.24	-0.36	0.01	0.37	interleukin 13
A_73_P046791	PDGFA	-1.33	-2.04	-2.54	0.00	-0.19	-3.50	-0.03	platelet-derived growth factor alpha polypeptide
A_73_115863	CD4	-1.39	-2.20	-1.92	-0.21	-0.57	-0.69	-0.20	CD4 molecule
Oxidative stress related genes
A_73_119453	GSR	4.19	3.59	0.47	0.93	0.85	-0.64	0.21	glutathione reductase
A_73_118238	DUSP16	2.02	1.72	-0.01	0.67	-0.85	0.14	0.42	dual specificity phosphatase 16
A_73_103760	GPX7	1.77	1.65	0.00	0.12	0.08	0.67	0.43	glutathione peroxidase 7
A_73_116548	HMOX1	1.74	1.65	1.17	1.66	0.55	2.86	0.26	hemeoxygenase (decycling) 1
A_73_P091051	TXNRD1	1.38	1.39	-0.55	1.23	0.40	-0.52	0.09	thioredoxinreductase 1
A_73_106948	GPX4	1.05	0.57	0.63	-0.19	-0.29	0.03	-0.14	glutathione peroxidase 4
A_73_P296471	SOD3	-1.18	-1.96	-1.72	0.72	0.12	-0.13	1.07	superoxide dismutase 3, extracellular