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Expression of α-SMA in the RPE of the WT and p27 KO retinas after photoreceptor damage. α-smooth muscle actin (α-SMA) immunolabeling is transiently increased in the RPE of the wild-type (WT) retinas with the peak around day 5 after N-methyl-N-nitrosourea (MNU) treatment. Note the absence of α-SMA labeling in the mutant retinas. MyoVIIa, myosin VIIa; Cont, control. Scale bar = 20 μm.
