Figure 4.
Microscopic fluorescence imaging of frozen tissue section from tumor (20X). DAPI (blue) staining illustrates nuclei (A). Strong, selective distribution of the G3-Curc nanoparticles (green) were visualized in tumor tissue (B). Overlays of fluorescence from the G3-Curc (green) and DAPI are shown in panel C. A high-resolution view showed accumulation of the G3-Curc within tumor cell nuclei validated by DAPI staining for viable cellularity.