TABLE 1.
In vivo and isolated cell load
| control | PMAD | |
|---|---|---|
| ESPVR (mmHg/μl) | 1.0±0.10 | 0.5±0.1 (p=0.02) |
| PRSW (mmHg) | 58±8 | 30±6 (p=0.02) |
| CI (mmHg/μl*s) | 93±6 | 64±6 (p=0.005) |
| τ (ms) | 12±3 | 45±6 (p=7e-11) |
| ESLTR (au) | 84±11 | 34±6 (p=0.04) |
| EDLTR (au) | 44±6 | 28±6 (p=0.02) |
| Peak PRSWcell (au) | 8±2 | 3.0±1 (p=0.006) |
ESPVR: end-systolic pressure volume relationship; PRSW: Preload Recruitable Stroke Work; CI: cardiac input; τ: isovolumic relaxation constant; ESLTR: end-systolic length-tension relationship; EDLTR: end-diastolic length-tension relationship.