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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Nature. 2016 Jun 15;534(7607):335–340. doi: 10.1038/nature18282

Figure 6. NSun2-deletion sensitizes tumour-initiating cells to cytotoxic stress.

Figure 6

a-c, Tumour size (mean ± s.e.m) (a) and Ki67 detection (b, c) in control (Ctr) or 5’FU-treated mice. d, K10 and Itgα6 detection in treated NSun2-/- tumours. Arrows: K10+/Itgα6+-positive cells. e, Tumour size in mice treated with 5’FU and/or angiogenin inhibitor (AI). f, Quantification of tumour-initiating cells in tumours shown in (e) (mean ± s.d.). *p < 0.05; **p< 0.01 (two-tailed Student’s t-test). n=mice. Scale bars: 100 μm. Source data: SI_Fig6.