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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Appl Toxicol. 2016 Mar 28;36(11):1446–1459. doi: 10.1002/jat.3300

Figure 1.

Figure 1

Arsenic inhibits RBL-2H3 cell degranulation following 1 hour exposure to DNP-BSA antigen (Ag). Effects of various concentrations of As on 1 hour, 0.00016 μg mL-1Ag-mediated degranulation were assessed as described (Hutchinson et al., 2011). In the absence of As, this antigen dose elicited an average absolute degranulation response of 12 ± 2% (SEM; ∼23% of the maximal response). Values represent means ± SEM for five independent experiments, where three replicates per dose were performed for each experiment. One-way ANOVA with Tukey's post-tests (compared to the 1 ppb sample) were performed using Graphpad Prism software; *p< 0.05, ***p< 0.001. This figure is reprinted from (Hutchinson et al., 2011) (Copyright 2010 John Wiley & Sons, Ltd.)